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O collagen biostimulator It naturally stimulates the production of collagen, elastin, and hyaluronic acid.
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It treats facial and body sagging, wrinkles, double chin, scars, and cellulite.
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Visible results between 2 and 3 months after application.
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Made in a doctor's office, with safety measures and products approved by Anvisa (Brazilian Health Regulatory Agency).
Schedule your personalized evaluation with Dr. Renata!
Table of Contents
What is a collagen biostimulator?
O collagen biostimulator It is an injectable substance that acts directly on the deeper layers of the skin, stimulating the cells responsible for the production of collagen and elastin.
This process improves firmness, elasticity and texture of the skin, combating sagging and signs of aging in a gradual and natural way.
Among the best-known biostimulating substances are:
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Poly-L-lactic acid (Sculptra®, Elleva®)
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Calcium hydroxyapatite (Radiesse®)
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Polycaprolactone (Ellansé®)
All are biocompatible and safe, with proven results in aesthetic dermatology.
How does collagen biostimulator work on the skin?
When applied to the deeper layers of the dermis, the biostimulator triggers a... controlled inflammatory response, which stimulates fibroblasts — the cells responsible for producing collagen, elastin, and hyaluronic acid.
As a result, the skin undergoes a process of cell renewal, than:
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Restores firmness and support.,
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It softens wrinkles and expression lines.,
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Improves skin texture and radiance.,
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It increases skin hydration and density..
The result is more even, firm, and rejuvenated skin, with a progressive effect that reaches its peak between 60 and 90 days after the procedure.
Radiesse
Promotional Price
Protocol including 1 syringe
1.890
3.590
O Radiesse is an collagen biostimulator made of calcium hydroxyapatite that improves the firmness, support and skin qualityIn addition to stimulating collagen, it provides a lifting effect, Redefining facial contours and leaving the skin more... dense, elastic and rejuvenated.
Values in Reais
sculptra
Promotional Price
Protocol including 1 vial
2.200
3.900
O sculptra is an collagen biostimulator that improves the skin laxity, firmness and density of the face and body. It acts gradually, stimulating the natural collagen production, smoothing wrinkles and restoring facial contours.
Values in Reais
Main benefits of collagen biostimulators
The treatment offers multiple advantages, both aesthetic and structural. Among the 10 main benefits, stand out:
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Global skin rejuvenation – It stimulates collagen and restores vitality.
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Reduction of facial and body sagging. – Improves contour and firmness.
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Smoothing of wrinkles and expression lines. – progressive and natural result.
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Improvement of nasolabial folds and wrinkles. – Restores volume without an artificial effect.
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Smoother and more luminous texture – even-toned skin with a more radiant appearance.
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Double chin reduction – It works to firm the neck and define the jawline.
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Cellulite reduction – It increases skin thickness and smooths out irregularities.
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Body firmness – ideal for arms, abdomen, thighs and buttocks.
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Scar improvement – especially acne and minor depressions.
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Hand rejuvenation – It softens wrinkles and restores volume.
How is the application done?
The procedure is performed in a doctor's office, in a safe and minimally invasive way.
The protocol follows simple and well-tolerated steps:
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Hygiene and local anesthesia, for the patient's complete comfort.
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Preparation of the substance, depending on the biostimulator chosen.
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Application with a cannula or fine needle., reaching the deeper layers of the skin.
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Light massage in the area., for uniform distribution of the product.
Each session lasts approximately 30 to 45 minutes...and the number of applications varies according to the type of biostimulator and the treatment objective — generally between... 2 and 4 sessions, at monthly intervals.
Where can the biostimulator be applied?
The treatment is versatile and can be performed in several areas:
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Face: It improves sagging skin, contour, and deep lines.
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Neck and chest: Treats fine wrinkles and uneven texture.
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Hands: It restores firmness and softens wrinkles.
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Arms: It reduces the "bye-bye" effect and improves elasticity.
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Abdomen: Ideal after pregnancy or weight loss.
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Thighs and buttocks: It improves sagging skin and the appearance of cellulite.
Types of collagen biostimulators
Each substance has specific characteristics and indications.
1. Poly-L-lactic acid (Sculptra®, Elleva®)
It stimulates type I collagen, promoting firmness and overall skin improvement.
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Duration: 12 to 24 months.
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Sessions: 3 to 4.
2. Calcium hydroxyapatite (Radiesse®)
It provides an immediate filling effect and stimulates collagen types I and III.
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Duration: 18 to 24 months.
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Sessions: 2 to 3.
3. Polycaprolactone (Ellansé®)
It offers long-lasting and even results, with gradual collagen production.
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Duration: 1 to 4 years.
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Sessions: usually 1.
Duration of results
The duration of effects varies depending on the substance used, but on average the results last between 12 and 24 months, which can reach 4 years with some types of biostimulators.
Annual maintenance sessions can prolong and intensify the effect.
Possible effects and contraindications
The treatment is safe and well-tolerated, but it can cause... mild redness, swelling, or minor bruising, which disappear in a few days.
More serious complications, such as nodules, are rare and usually associated with improper application.
The procedure is not indicated to:
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Pregnant or breastfeeding women.
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Under 18 years of age.
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People with active autoimmune diseases or skin infections.
Therefore, it is essential that the application be made by experienced dermatologist, using the correct technique and an original product.
Safety and support at the Renata Ralha Clinic
Na Renata Ralha Clinic, the collagen biostimulators They are applied with technical rigor, cutting-edge technology, and personalized medical monitoring.
A Dr. Renata Ralha (CRM 52-84102-1 | RQE 28115), dermatologist with specialist certification from Brazilian Society of Dermatology (SBD), performs individualized protocols according to the patient's skin type, degree of sagging, and goals.
Each stage of treatment — before, during, and after — is closely monitored to ensure safety, predictability, and progressive and harmonious results.
Conclusion
O collagen biostimulator It is one of the most comprehensive treatments for Rejuvenate the skin and restore firmness naturally and lastingly..
With proven results and high biocompatibility, it stimulates collagen from the inside out, promoting... firmer, more elastic and rejuvenated skin, without surgery and without disruption to routine.
Schedule your evaluation at Renata Ralha Clinic and discover which biostimulator is ideal for your skin.
With personalized protocols, medical technology, and ethical monitoring, the treatment restores firmness, density, and luminosity to the skin, with subtle and elegant results.
Schedule an evaluation at Renata Ralha Clinic and discover the ideal protocol for your skin type.
Medical evaluation is essential to understand the patient's complaints, identify dermatological problems, and consider their individual characteristics, such as anatomy, skin type, and reactions to substances used. Based on this, it is possible to determine the appropriate techniques to naturally enhance the features of the face, skin, and body.
Choosing a dermatologist is crucial for a thorough analysis of the areas of disharmony in the patient and to determine the necessary techniques, whether it be increasing volume, correcting angles, or symmetry. With a personalized and exclusive treatment plan, it is possible to meet the specific needs of each patient while respecting their limitations.
Dr. Renata Ralha, Clinical, Aesthetic and Hair Dermatologist, CRM: 52-84102-1 RJ, RQE No.: 28115
Medical evaluation is essential to understand the patient's complaints, identify dermatological problems, and consider their individual characteristics, such as anatomy, skin type, and reactions to substances used. Based on this, it is possible to determine the appropriate techniques to naturally enhance the features of the face, skin, and body.
Choosing a dermatologist is crucial for a thorough analysis of the areas of disharmony in the patient and to determine the necessary techniques, whether it be increasing volume, correcting angles, or symmetry. With a personalized and exclusive treatment plan, it is possible to meet the specific needs of each patient while respecting their limitations.
Dr. Renata Ralha, Clinical, Aesthetic and Hair Dermatologist, CRM: 52-84102-1 RJ, RQE No.: 28115
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Do I need an evaluation before applying biostimulators?
Yes. A medical evaluation determines if there is a real indication and which protocol is most effective and safe.
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Can I choose the product (Sculptra, Radiesse, or Profhilo)?
The choice is made jointly, considering objectives, desired response time, and skin characteristics.
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How long does the evaluation take?
Usually between 30 and 45 minutes, with a detailed explanation of the proposed plan.
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Can I combine biostimulators with other technologies?
Yes. Often, combinations with CoolFase or Liftera optimize collagen stimulation, as determined by a medical professional.

